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Tetrasodium EDTA

Tetrasodium EDTA is the salt resulting from the neutralization of ethylenediaminetetraacetic acid (EDTA) with four equivalents of sodium hydroxide (or an equivalent sodium base). It is a white solid, highly soluble in water. Commercial samples often come hydrated, e.g., Na4EDTA·4H2O. Solutions derived from both anhydrous and hydrated forms exhibit the same properties at the same pH.

It serves as a source for the chelating agent EDTA4-. A 1% aqueous solution has a pH of about 11.3. When dissolved in neutral water, it partially converts to H2EDTA2-. Ethylenediaminetetraacetic acid is commercially produced through the intermediacy of tetrasodium EDTA.

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Uses in Cosmetics

Tetrasodium EDTA exhibits various effects and applications, including:

Acting as a chelating agent, it forms stable complexes with metal ions, preventing the catalytic decomposition of products by metal ions in cosmetics.
Helps to maintain cleanliness and stability of cosmetics, enhancing product shelf life.
In hair and skin care products, it improves product tolerance to metal ions, maintaining product performance.

Source 

Tetrasodium EDTA is obtained by neutralizing EDTA with sodium hydroxide.
Produced by mixing EDTA with four equivalents of sodium hydroxide and heating to hydrate, resulting in the hydrated form of Tetrasodium EDTA.

Globally Harmonized System of Classification and Labelling of Chemicals 

Tetrasodium EDTA, when used as a cosmetic additive at recommended concentrations, is safe and poses no harm to humans.

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