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Dipalmitoyl Hydroxyproline

Dipalmitoyl Hydroxyproline, an oil-soluble derivative of hydroxyproline, is the primary amino acid found in the collagen of the skin. Making it oil-soluble enhances its ability to penetrate the skin and lips effectively, signaling the uppermost layers to repair its supportive structures, which leads to a reduction in visible lines and wrinkles. Considered a signal peptide, it improves skin affinity when combined with oils or glycols. Besides supporting skin collagen, it also inhibits collagen-degrading enzymes known as matrix metalloproteinases, preventing collagen weakening and consequent sagging and thinning of lips.

二棕櫚酰羥脯氨酸, Dipalmitoyl Hydroxyproline, 化妝品 添加物, 化妝品 成分, 保養品 成分, 保養品 添加物, 抗衰老, 保濕, 膠原蛋白支持, 皮膚緊致, 減少細紋皺紋, 皮膚彈性, 安全性高, EWG低風險成分


Uses in Cosmetics

Dipalmitoyl Hydroxyproline has multiple effects and applications in cosmetics, including:

Enhancing skin hydration
Anti-aging, reducing fine lines and wrinkles
Supporting and strengthening the structure of skin collagen
Counteracting collagen-degrading enzymes, helping maintain skin elasticity and firmness


Derived from hydroxyproline, which is produced by the hydroxylation of the amino acid proline, requiring vitamin C as a cofactor
Synthesized through a chemical reaction between palmitic acid and hydroxyproline

Globally Harmonized System of Classification and Labelling of Chemicals 




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